Pharmaceutical Company

ProHub Comment

This is an excellent strategic decision-making case that tests the candidate's ability to disaggregate markets, identify relevant competitive segments, and systematically evaluate options based on value drivers. The case rewards structured thinking, hypothesis-driven questioning, and the ability to identify that selling costs and market access are the critical decision factors. The interviewer provides data progressively based on candidate questions, requiring the candidate to actively lead the analysis rather than passively receiving information.

Estimated Time 15 minutes
Difficulty Medium
Source Harvard
50 / 100

Our client is the U.S. pharmaceutical division of a multi-national corporation. In about six months the division will receive FDA approval to launch an anti-depressant drug. Despite this apparent good news from the FDA, the U.S. division is not elated. It has concerns over the market potential for this drug and its ability to reach the key prescribers in this therapeutic category. We have been asked to help determine whether they should 1) launch alone, 2) co-market with a partner, or 3) sell, license or swap the drug.

The concerns over market potential center on whether the drug can gain adequate competitive advantage in a market segment having two dominant, patent-protected competitors and nearly 100 generic competitors. Additionally, a higher technology antidepressant, which appears to offer therapeutic advantages, was recently introduced by a competitor.

Gaining the professional endorsement of psychiatrists is crucial to success in this therapeutic category since they write approximately half of the prescriptions for antidepressants. However, the division has no experience marketing drugs to this physician group. Consequently, it would have to hire a sales force and/or enter into a co-marketing agreement to gain access to psychiatrists through someone else’s force. The client would be able to leverage its existing sales force to reach the other half of the prescribers (Internal Medicine Specialist and Family and General Practitioners).

How would you help them decide whether to 1) launch alone, 2) co-market with a partner, or 3) sell, license or swap the drug to a third party?

Clarifying Information

Information is provided through interviewer responses during the case discussion rather than in a separate section. Key data points revealed include:

  1. The overall antidepressant drug market is $1.1 billion per year and growing above population growth rate
  2. The market is segmented by technology; the client’s product uses tricyclic antidepressants
  3. The tricyclic segment is declining due to substitution by new technology
  4. Market leader in tricyclic segment has ~10% share; number two has ~4%; remaining 100 competitors each have <2%
  5. New technology has captured 20% of total antidepressant market
  6. Client’s product is similar to number two competitor, slightly inferior to number one, and slightly better than generics
  7. Cost of goods sold is approximately 20% of net sales
  8. Selling expense is the largest component of remaining costs
  9. Psychiatrists prescribe approximately 50% of antidepressants and are key influencers
  10. Psychiatrists must endorse the drug before Internal Medicine/General Practitioner colleagues will endorse it