University researchers in Uganda developed a malaria vaccine and partnered with David-Wilson Limited (Ghana) for manufacturing and distribution with a breakeven model. The question is whether to launch. Analysis shows Ghana is viable (~62.5% market share needed), Uganda is challenging (~80% needed), and Tanzania is impossible (>100%). Competitive advantages include superior efficacy (95% vs 87% and 80%) but pricing remains a weakness in Uganda.
Key Insights:
- Market sizing requires converting local currencies to USD for fair comparison across countries
- Breakeven analysis must factor in both annual demand (based on case incidence and purchase rates) and fixed setup costs to determine required market share
- High fixed costs relative to market size can make markets unattractive despite large disease burden (South Africa example)
- Product quality/efficacy differentiation is valuable but may not overcome pricing disadvantages in price-sensitive markets
- Go-to-market strategy should include alternative partners or funding models (NGOs, government) to address cost competitiveness gaps